Muscle and stem cells: Muscle homeostasis

Muscle and stem cells: Muscle homeostasis


Skeletal muscles are responsible for
the voluntary movement of the body. They are composed of
fascicles containing multiple muscle fibres where
each represents a single cell. Individual myofibers are covered by
a basement membrane which is continuous with the
endomysium connective tissue layer. Peeling away
the basement membrane reveals myofibers and
the skeletal muscle stem cells, also known as
satellite cells. They play a critical role
in muscle fibre repair. Peeling away the sarcolemma membrane
of the myofiber reveals the intracellular components,
including myonuclei that originate from the fusion of hundreds of myoblasts. The myosin and actin contractile structure gives us the ability to move
in a controlled manner.

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