Protein Folding

Protein Folding

Proteins are building blocks that that help
give your body structure and do work around your body. They move molecules, they make new molecules,
they recycle old molecules, and this is just to name a few of the things that they do. But maybe the most interesting thing is that
these protein building blocks are themselves made up of smaller building blocks called
amino acids. Here you see a string of amino acids. The different shapes that you can see represent
the atoms that make up each amino acid. And here we’ve highlighted 12 individual
amino acids. To make it simpler, each different amino acid
can be represented by a single letter. Now, each amino acid is shown as a colored
ball, looking like beads on a string. This makes the protein’s structure easier
to imagine. The order of amino acids is only part of the
story. Because of the different shapes of the individual
amino acids, they like to fold into even more interesting 3 dimensional shapes. This molecule is twisting into several different
spiral or helical shapes and then those are folding on each other. Take a look at the three dimensional shape
as we give the protein a spin. Looks kind of like logs stacked in a fireplace. Here is the one letter amino acid code revealing
the identity of each amino acid. Again now you see the amino acids drawn to
show the position of each atom. This is like looking at an atomic skeleton
of each amino acid. Just like you take up more space than just
your skeleton would, see how much space each atom really occupies. This is the real shape of the protein. Now we’ve seen an example of a protein taking
shape, and several of the ways scientists visualize these tiny building blocks used
throughout your body.

6 Replies to “Protein Folding”

  1. Commentary is helpful, but a little cheesy. :/ It would be nice if it went a little more in depth, most people learning about this probably need to know what happens to cause the protein to fold (specific amino acid arranement, hydrogen bonds, etc). Also would be helpful to describe the different levels of protein organization shown here: primary, secondary and tertiary. I appreciate you taking time to do something like this though.

  2. This was really helpful in visualizing the folding process happen instead of just reading it out of a textbook.

  3. Good vid, I just subscribed, keep it goin. I'm trying to grow my channel too, it's hard but it's still fun. Peace!

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